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The interplay between tissue plasminogen activator domains and fibrin structures in the regulation of fibrinolysis: kinetic and microscopic studies

Regulation of tissue-type plasminogen activator (tPA) depends on fibrin binding and fibrin structure. tPA structure/function relationships were investigated in fibrin formed by high or low thrombin concentrations to produce a fine mesh and small pores, or thick fibers and coarse structure, respectiv...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Longstaff, Colin, Thelwell, Craig, Williams, Stella C., Silva, Marta M. C. G., Szabó, László, Kolev, Krasimir
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031486/
https://ncbi.nlm.nih.gov/pubmed/20966169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-290338
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