Macrophage Epithelial Reprogramming Underlies Mycobacterial Granuloma Formation and Promotes Infection

Mycobacterium tuberculosis infection in humans triggers formation of granulomas, tightly organized immune cell aggregates that are the central structure of tuberculosis. Infected and uninfected macrophages interdigitate, assuming an altered, flattened appearance. Although pathologists have described...

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Bibliografiska uppgifter
I publikationen:Immunity
Huvudupphovsmän: Cronan, Mark R., Beerman, Rebecca W., Rosenberg, Allison F., Saelens, Joseph W., Johnson, Matthew G., Oehlers, Stefan H., Sisk, Dana M., Jurcic Smith, Kristen L., Medvitz, Neil A., Miller, Sara E., Trinh, Le A., Fraser, Scott E., Madden, John F., Turner, Joanne, Stout, Jason E., Lee, Sunhee, Tobin, David M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268069/
https://ncbi.nlm.nih.gov/pubmed/27760340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.09.014
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