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Mammalian target of Rapamycin inhibition and mycobacterial survival are uncoupled in murine macrophages
BACKGROUND: Autophagy is a cellular response to intracellular pathogens including mycobacteria and is induced by the direct inhibitors of mammalian target of Rapamycin (mTOR), a major negative regulator of autophagy. Autophagy induction by mTOR inhibition (mTOR dependent autophagy), through chemical...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937017/ https://ncbi.nlm.nih.gov/pubmed/24528777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-15-4 |
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