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An Explant Technique for High-Resolution Imaging and Manipulation of Mycobacterial Granulomas

A central and critical structure in tuberculosis, the mycobacterial granuloma consists of highly organized immune cells, including macrophages that drive granuloma formation through a characteristic epithelioid transformation. Difficulties in imaging within intact animals as well as the inherent cav...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Cronan, Mark R., Matty, Molly A., Rosenberg, Allison F., Blanc, Landry, Pyle, Charlie J., Espenschied, Scott T., Rawls, John F., Dartois, Véronique, Tobin, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312189/
https://ncbi.nlm.nih.gov/pubmed/30504889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0215-8
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