HIV induces expression of complement component C3 in astrocytes by NF-κB-dependent activation of interleukin-6 synthesis

BACKGROUND: Abnormal activation of the complement system contributes to some central nervous system diseases but the role of complement in HIV-associated neurocognitive disorder (HAND) is unclear. METHODS: We used real-time PCR and immunohistochemistry to detect complement expression in postmortem b...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Nitkiewicz, Jadwiga, Borjabad, Alejandra, Morgello, Susan, Murray, Jacinta, Chao, Wei, Emdad, Luni, Fisher, Paul B., Potash, Mary Jane, Volsky, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267445/
https://ncbi.nlm.nih.gov/pubmed/28122624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0794-9
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