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Mechanism of Ceftriaxone Induction of Excitatory Amino Acid Transporter-2 Expression and Glutamate Uptake in Primary Human Astrocytes

Glutamate is an essential neurotransmitter regulating brain functions. Excitatory amino acid transporter (EAAT)-2 is one of the major glutamate transporters primarily expressed in astroglial cells. Dysfunction of EAAT2 is implicated in acute and chronic neurological disorders, including stroke/ische...

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Detalhes bibliográficos
Main Authors: Lee, Seok-Geun, Su, Zhao-Zhong, Emdad, Luni, Gupta, Pankaj, Sarkar, Devanand, Borjabad, Alejandra, Volsky, David J., Fisher, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442320/
https://ncbi.nlm.nih.gov/pubmed/18326497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707697200
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