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Astrocyte elevated gene-1 (AEG-1) functions as an oncogene and regulates angiogenesis
Astrocyte-elevated gene-1 (AEG-1) expression is increased in multiple cancers and plays a central role in Ha-ras-mediated oncogenesis through the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway. Additionally, overexpression of AEG-1 protects primary and transformed human and rat cells fro...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2795510/ https://ncbi.nlm.nih.gov/pubmed/19940250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910936106 |
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