Inversion of the Vδ1 to Vδ2 γδ T cell ratio in CVID is not restored by IVIg and is associated with immune activation and exhaustion

Common variable immunodeficiency (CVID) is defined by low levels of IgG and IgA, but perturbations in T cells are also commonly found. However, there is limited information on γδ T cells in CVID patients. Newly diagnosed CVID patients (n = 15) were enrolled before and after intravenous IgG (IVIg) re...

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Udgivet i:Medicine (Baltimore)
Main Authors: Paquin-Proulx, Dominic, Barsotti, Nathália Silveira, Santos, Bianca A. N., Marinho, Ana Karolina B. B., Kokron, Cristina M., Carvalho, Karina I., Barros, Myrthes T., Kalil, Jorge, Nixon, Douglas F., Kallas, Esper G.
Format: Artigo
Sprog:Inglês
Udgivet: Wolters Kluwer Health 2016
Fag:
3600
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5265843/
https://ncbi.nlm.nih.gov/pubmed/27472706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000004304
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