Inversion of the Vδ1 to Vδ2 γδ T cell ratio in CVID is not restored by IVIg and is associated with immune activation and exhaustion

Common variable immunodeficiency (CVID) is defined by low levels of IgG and IgA, but perturbations in T cells are also commonly found. However, there is limited information on γδ T cells in CVID patients. Newly diagnosed CVID patients (n = 15) were enrolled before and after intravenous IgG (IVIg) re...

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Publicat a:Medicine (Baltimore)
Autors principals: Paquin-Proulx, Dominic, Barsotti, Nathália Silveira, Santos, Bianca A. N., Marinho, Ana Karolina B. B., Kokron, Cristina M., Carvalho, Karina I., Barros, Myrthes T., Kalil, Jorge, Nixon, Douglas F., Kallas, Esper G.
Format: Artigo
Idioma:Inglês
Publicat: Wolters Kluwer Health 2016
Matèries:
3600
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5265843/
https://ncbi.nlm.nih.gov/pubmed/27472706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000004304
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