Inversion of the Vδ1 to Vδ2 γδ T cell ratio in CVID is not restored by IVIg and is associated with immune activation and exhaustion

Common variable immunodeficiency (CVID) is defined by low levels of IgG and IgA, but perturbations in T cells are also commonly found. However, there is limited information on γδ T cells in CVID patients. Newly diagnosed CVID patients (n = 15) were enrolled before and after intravenous IgG (IVIg) re...

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Gepubliceerd in:Medicine (Baltimore)
Hoofdauteurs: Paquin-Proulx, Dominic, Barsotti, Nathália Silveira, Santos, Bianca A. N., Marinho, Ana Karolina B. B., Kokron, Cristina M., Carvalho, Karina I., Barros, Myrthes T., Kalil, Jorge, Nixon, Douglas F., Kallas, Esper G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Wolters Kluwer Health 2016
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3600
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5265843/
https://ncbi.nlm.nih.gov/pubmed/27472706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000004304
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