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Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-β enhancer

Transcriptional activation of the interferon-β (IFN-β) gene requires assembly of an enhanceosome containing the transcription factors ATF-2/c-Jun, IRF-3/IRF-7, NF-κB and HMGI(Y). These factors cooperatively bind a composite DNA site and activate expression of the IFN-β gene. The 3.0 Å crystal struct...

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Bibliografski detalji
Izdano u:EMBO J
Glavni autori: Panne, Daniel, Maniatis, Tom, Harrison, Stephen C
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2004
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC526468/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15510218/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600453
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