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Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-β enhancer
Transcriptional activation of the interferon-β (IFN-β) gene requires assembly of an enhanceosome containing the transcription factors ATF-2/c-Jun, IRF-3/IRF-7, NF-κB and HMGI(Y). These factors cooperatively bind a composite DNA site and activate expression of the IFN-β gene. The 3.0 Å crystal struct...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC526468/ https://ncbi.nlm.nih.gov/pubmed/15510218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600453 |
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