Stochastic Expression of the Interferon-β Gene

Virus infection of mammalian cells induces the production of high levels of type I interferons (IFNα and β), cytokines that orchestrate antiviral innate and adaptive immunity. Previous studies have shown that only a fraction of the infected cells produce IFN. However, the mechanisms responsible for...

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Main Authors: Zhao, Mingwei, Zhang, Jiangwen, Phatnani, Hemali, Scheu, Stefanie, Maniatis, Tom
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265471/
https://ncbi.nlm.nih.gov/pubmed/22291574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001249
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