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Negative Regulation of Interferon-β Gene Expression during Acute and Persistent Virus Infections

The production of type I interferons (IFNs) in response to viral infections is critical for antiviral immunity. However, IFN production is transient, and continued expression can lead to inflammatory or autoimmune diseases. Thus, understanding the mechanisms underlying the negative regulation of IFN...

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Hlavní autoři: Ye, Junqiang, Maniatis, Tom
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108996/
https://ncbi.nlm.nih.gov/pubmed/21677781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020681
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