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Binding site for Robo receptors revealed by dissection of the leucine-rich repeat region of Slit

Recognition of the large secreted protein Slit by receptors of the Robo family provides fundamental signals in axon guidance and other developmental processes. In Drosophila, Slit–Robo signalling regulates midline crossing and the lateral position of longitudinal axon tracts. We report the functiona...

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Autores principales: Howitt, Jason A, Clout, Naomi J, Hohenester, Erhard
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC526463/
https://ncbi.nlm.nih.gov/pubmed/15496984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600446
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