Selection of chemically defined media for CHO cell fed-batch culture processes

Two CHO cell clones derived from the same parental CHO(BC®) cell line and producing the same monoclonal antibody (BC-G, a low producing clone; BC-P, a high producing clone) were tested in four basal media in all possible combinations with three feeds (=12 conditions) in fed-batch cultures. Higher am...

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Vydáno v:Cytotechnology
Hlavní autoři: Pan, Xiao, Streefland, Mathieu, Dalm, Ciska, Wijffels, René H., Martens, Dirk E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264622/
https://ncbi.nlm.nih.gov/pubmed/27900626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-016-0036-5
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