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Metabolic characterization of a CHO cell size increase phase in fed-batch cultures

Normally, the growth profile of a CHO cell fed-batch process can be divided into two main phases based on changes in cell concentration, being an exponential growth phase and a stationary (non-growth) phase. In this study, an additional phase is observed during which the cell division comes to a hal...

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Vydáno v:Appl Microbiol Biotechnol
Hlavní autoři: Pan, Xiao, Dalm, Ciska, Wijffels, René H., Martens, Dirk E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656727/
https://ncbi.nlm.nih.gov/pubmed/28951949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-017-8531-y
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