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Increasing batch-to-batch reproducibility of CHO cultures by robust open-loop control
In order to guarantee the quality of recombinant therapeutic proteins produced in mammalian cell systems, the straightforward approach in industry is to run the processes as reproducible as possible. It is first shown that considerable distortions in the currently operated processes appear when the...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer Netherlands
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021148/ https://ncbi.nlm.nih.gov/pubmed/21057872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-010-9320-y |
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