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Immunological and clinical significance of HLA class I antigen processing machinery component defects in malignant cells

Experimental as well as clinical studies demonstrate that the immune system plays a major role in controlling generation and progression of tumors. The cancer immunoediting theory supports the notion that tumor cell immunogenicity is dynamically shaped by the immune system, as it eliminates immunoge...

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Bibliographic Details
Published in:Oral Oncol
Main Authors: Concha-Benavente, Fernando, Srivastava, Raghvendra, Ferrone, Soldano, Ferris, Robert L.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264518/
https://ncbi.nlm.nih.gov/pubmed/27264839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2016.05.008
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