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Immunological and clinical significance of HLA class I antigen processing machinery component defects in malignant cells

Experimental as well as clinical studies demonstrate that the immune system plays a major role in controlling generation and progression of tumors. The cancer immunoediting theory supports the notion that tumor cell immunogenicity is dynamically shaped by the immune system, as it eliminates immunoge...

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Detalles Bibliográficos
Publicado en:Oral Oncol
Main Authors: Concha-Benavente, Fernando, Srivastava, Raghvendra, Ferrone, Soldano, Ferris, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264518/
https://ncbi.nlm.nih.gov/pubmed/27264839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2016.05.008
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