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Immunological and clinical significance of HLA class I antigen processing machinery component defects in malignant cells

Experimental as well as clinical studies demonstrate that the immune system plays a major role in controlling generation and progression of tumors. The cancer immunoediting theory supports the notion that tumor cell immunogenicity is dynamically shaped by the immune system, as it eliminates immunoge...

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Detalhes bibliográficos
Publicado no:Oral Oncol
Main Authors: Concha-Benavente, Fernando, Srivastava, Raghvendra, Ferrone, Soldano, Ferris, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264518/
https://ncbi.nlm.nih.gov/pubmed/27264839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2016.05.008
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