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The neurotrophin receptor p75 mediates gp120-induced loss of synaptic spines in aging mice

Human immunodeficiency virus 1 and its envelope protein gp120 reduce synaptodendritic complexity. However, the mechanisms contributing to this pathological feature are still not understood. The proneurotrophin brain-derived neurotrophic factor promotes synaptic simplification through the activation...

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Publicat a:Neurobiol Aging
Autors principals: Bachis, Alessia, Wenzel, Erin, Boelk, Allyssia, Becker, Jodi, Mocchetti, Italo
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264514/
https://ncbi.nlm.nih.gov/pubmed/27498053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.07.001
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