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Two Drosophila suppressors of cytokine signaling (SOCS) differentially regulate JAK and EGFR pathway activities

BACKGROUND: The Janus kinase (JAK) cascade is an essential and well-conserved pathway required to transduce signals for a variety of ligands in both vertebrates and invertebrates. While activation of the pathway is essential to many processes, mutations from mammals and Drosophila demonstrate that r...

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Bibliografiske detaljer
Main Authors: Rawlings, Jason S, Rennebeck, Gabriela, Harrison, Susan MW, Xi, Rongwen, Harrison, Douglas A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC526380/
https://ncbi.nlm.nih.gov/pubmed/15488148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-5-38
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