GABA(A) receptor occupancy by subtype selective GABA(Aα2,3) modulators: PET studies in humans

RATIONALE: Sedation, dependence, and abuse liability limit the use of non-selective γ-aminobutyric acid (GABA(A)) receptor positive modulators for the treatment of anxiety. AZD7325 and AZD6280 are novel, subtype-selective GABA(Aα2,3) receptor positive modulators with limited sedative effects. OBJECT...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Psychopharmacology (Berl)
Glavni autori: Jucaite, Aurelija, Cselényi, Zsolt, Lappalainen, Jaakko, McCarthy, Dennis J., Lee, Chi-Ming, Nyberg, Svante, Varnäs, Katarina, Stenkrona, Per, Halldin, Christer, Cross, Alan, Farde, Lars
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2016
Teme:
Original Investigation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5263201/
https://ncbi.nlm.nih.gov/pubmed/28013354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-016-4506-4
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items