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Sindbis virus RNA polymerase is degraded by the N-end rule pathway.

Upon infection of animal cells by Sindbis virus, four nonstructural (ns) proteins, termed nsP1-4 in order from 5' to 3' in the genome, are produced by posttranslational cleavage of a polyprotein. nsP4 is believed to function as the viral RNA polymerase and is short-lived in infected cells. We show h...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: de Groot, R J, Rümenapf, T, Kuhn, R J, Strauss, E G, Strauss, J H
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52632/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1924357/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.20.8967
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