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The N-end rule: functions, mysteries, uses.

The N-end rule relates the in vivo half-life of a protein to the identity of its N-terminal residue. Similar but distinct versions of the N-end rule operate in all organisms examined, from mammals to fungi and bacteria. In eukaryotes, the N-end rule pathway is a part of the ubiquitin system. I discu...

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
1. Verfasser: Varshavsky, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1996
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC37957/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8901547/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.22.12142
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