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Deletion of Nlrp3 Augments Survival During Polymicrobial Sepsis by Decreasing Autophagy and Enhancing Phagocytosis

NLRP3 inflammasome is a critical player in innate immunity. Neutrophil recruitment to tissues and effective function of neutrophils are critical innate immune function to bacterial clearance. However, the role of NLRP3 in neutrophil-dependent bacterial clearance in polymicrobial sepsis is unclear. H...

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Bibliografische gegevens
Gepubliceerd in:J Immunol
Hoofdauteurs: Liliang, Jin, Batra, Sanjay, Jeyaseelan, Samithamby
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5263118/
https://ncbi.nlm.nih.gov/pubmed/28031338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601745
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