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Deletion of Nlrp3 Augments Survival During Polymicrobial Sepsis by Decreasing Autophagy and Enhancing Phagocytosis

NLRP3 inflammasome is a critical player in innate immunity. Neutrophil recruitment to tissues and effective function of neutrophils are critical innate immune function to bacterial clearance. However, the role of NLRP3 in neutrophil-dependent bacterial clearance in polymicrobial sepsis is unclear. H...

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Detalhes bibliográficos
Publicado no:J Immunol
Principais autores: Liliang, Jin, Batra, Sanjay, Jeyaseelan, Samithamby
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5263118/
https://ncbi.nlm.nih.gov/pubmed/28031338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601745
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