Cabotegravir Long-Acting Injection Protects Macaques against Intravenous Challenge with SIVmac251

OBJECTIVE: We evaluated the effectiveness of cabotegravir (CAB; GSK1265744 or GSK744) long-acting (LA) as pre-exposure prophylaxis (PrEP) against intravenous SIV challenge in a model that mimics blood transfusions based on the per-act probability of infection. DESIGN: CAB LA is an InSTI formulated a...

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Pubblicato in:AIDS
Autori principali: Andrews, Chasity D., Bernard, Leslie ST., Poon, Amanda Yee, Mohri, Hiroshi, Gettie, Natanya, Spreen, William R., Gettie, Agegnehu, Russell-Lodrigue, Kasi, Blanchard, James, Hong, Zhi, Ho, David D., Markowitz, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5263045/
https://ncbi.nlm.nih.gov/pubmed/27902508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001343
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