Generation of Lineage-Related, Mucosally Transmissible Subtype C R5 Simian-Human Immunodeficiency Viruses Capable of AIDS Development, Induction of Neurological Disease, and Coreceptor Switching in Rhesus Macaques

Most human immunodeficiency virus (HIV) transmissions are initiated with CCR5 (R5)-using viruses across mucosal surfaces, with the majority in regions where HIV type 1 (HIV-1) clade C predominates. Mucosally transmissible, highly replication competent, pathogenic R5 simian-human immunodeficiency vir...

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Autori principali: Ren, Wuze, Mumbauer, Alexandra, Gettie, Agegnehu, Seaman, Michael S., Russell-Lodrigue, Kasi, Blanchard, James, Westmoreland, Susan, Cheng-Mayer, Cecilia
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648099/
https://ncbi.nlm.nih.gov/pubmed/23514895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00178-13
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