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Intra-tumor delivery of zoledronate mitigates metastasis-induced osteolysis superior to systemic administration

Bisphosphonates (BPs) have recently been shown to have direct anti-tumor properties. Systemic treatment with BPs can have multiple adverse effects such as osteonecrosis of the jaw and BP induced bone fracturing and spine instability. While benefits of systemic BP treatments may outweigh risks, local...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Bone Oncol
मुख्य लेखकों: Nooh, Anas, Zhang, Yu Ling, Sato, Daisuke, Rosenzweig, Derek H., Tabariès, Sébastien, Siegel, Peter, Barralet, Jake E., Weber, Michael H.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5262502/
https://ncbi.nlm.nih.gov/pubmed/28138422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbo.2017.01.001
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