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A Double Allylation Strategy for Gram-Scale Guaianolide Production: Total Synthesis of (+)-Mikanokryptin

With over 5000 members isolated to date, sesquiterpene lactones represent a prolific source of medicinal agents with several derivatives in human clinical trials. The guaianolides, a major subset of this group, have been intensely investigated from both medicinal and chemical synthesis perspectives...

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Bibliografski detalji
Izdano u:Angew Chem Int Ed Engl
Glavni autori: Hu, Xirui, Xu, Silong, Maimone, Thomas J.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5262430/
https://ncbi.nlm.nih.gov/pubmed/28052523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201611078
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