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Four-Step Synthesis of the Antimalarial Cardamom Peroxide via an Oxygen Stitching Strategy

[Image: see text] A four-step synthesis of the antimalarial terpene cardamom peroxide, a 1,2-dioxepane-containing natural product, is reported from (−)-myrtenal and molecular oxygen. This highly concise route was guided by biosynthetic logic and enabled by an unusual manganese-catalyzed, tandem hydr...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Hu, Xirui, Maimone, Thomas J.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353017/
https://ncbi.nlm.nih.gov/pubmed/24673099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja502208z
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