Alzheimer beta/A4 amyloid precursor protein in human brain: aging-associated increases in holoprotein and in a proteolytic fragment.

Alzheimer beta/A4 amyloid precursor protein (APP) has been suggested to play a central role in the pathogenesis of Alzheimer disease. We have measured the content of different species of APP holoprotein and carboxyl-terminal fragments in human brains from young individuals, nondemented aged individu...

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Detalhes bibliográficos
Main Authors: Nordstedt, C, Gandy, S E, Alafuzoff, I, Caporaso, G L, Iverfeldt, K, Grebb, J A, Winblad, B, Greengard, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC52620/
https://ncbi.nlm.nih.gov/pubmed/1924350
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