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Targeted Imaging of the Atypical Chemokine Receptor 3 (ACKR3/CXCR7) in Human Cancer Xenografts

The atypical chemokine receptor ACKR3 (formerly CXCR7), overexpressed in various cancers compared to normal tissues, plays a pivotal role in adhesion, angiogenesis, tumorigenesis, metastasis and tumor cell survival. ACKR3 modulates the tumor microenvironment and regulates tumor growth. The therapeut...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Nucl Med
Hauptverfasser: Azad, Babak Behnam, Lisok, Ala, Chatterjee, Samit, Poirier, John T., Pullambhatla, Mrudula, Luker, Gary D., Pomper, Martin G., Nimmagadda, Sridhar
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5261856/
https://ncbi.nlm.nih.gov/pubmed/26912435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.115.167932
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