Bridged Cyclams as Imaging Agents for Chemokine Receptor 4 (CXCR4)

Over-expression of chemokine receptor 4 (CXCR4) is present in a majority of cancers, has been linked to an aggressive phenotype, and may indicate the metastatic potential of primary tumor. Several CXCR4 targeted therapeutics are in clinical trials and the development of the corresponding imaging age...

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Detalhes bibliográficos
Main Authors: Woodard, Lauren E., De Silva, Ravindra A., Azad, Babak Behnam, Lisok, Ala, Pullambhatla, Mrudula, Lesniak, Wojciech, Mease, Ronnie C., Pomper, Martin G., Nimmagadda, Sridhar
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104431/
https://ncbi.nlm.nih.gov/pubmed/25038987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2014.04.081
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