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Structural Characterization and in Vivo Evaluation of β-Hairpin Peptidomimetics as Specific CXCR4 Imaging Agents

[Image: see text] The CXCR4 chemokine receptor is integral to several biological functions and plays a pivotal role in the pathophysiology of many diseases. As such, CXCR4 is an enticing target for the development of imaging and therapeutic agents. Here we report the evaluation of the POL3026 peptid...

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Podrobná bibliografie
Vydáno v:Mol Pharm
Hlavní autoři: Lesniak, Wojciech G., Sikorska, Emilia, Shallal, Hassan, Azad, Babak Behnam, Lisok, Ala, Pullambhatla, Mrudula, Pomper, Martin G., Nimmagadda, Sridhar
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612581/
https://ncbi.nlm.nih.gov/pubmed/25590535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500799q
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