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Structural Characterization and in Vivo Evaluation of β-Hairpin Peptidomimetics as Specific CXCR4 Imaging Agents

[Image: see text] The CXCR4 chemokine receptor is integral to several biological functions and plays a pivotal role in the pathophysiology of many diseases. As such, CXCR4 is an enticing target for the development of imaging and therapeutic agents. Here we report the evaluation of the POL3026 peptid...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Lesniak, Wojciech G., Sikorska, Emilia, Shallal, Hassan, Azad, Babak Behnam, Lisok, Ala, Pullambhatla, Mrudula, Pomper, Martin G., Nimmagadda, Sridhar
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612581/
https://ncbi.nlm.nih.gov/pubmed/25590535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500799q
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