Using Genetic Variation to Explore the Causal Effect of Maternal Pregnancy Adiposity on Future Offspring Adiposity: A Mendelian Randomisation Study

BACKGROUND: It has been suggested that greater maternal adiposity during pregnancy affects lifelong risk of offspring fatness via intrauterine mechanisms. Our aim was to use Mendelian randomisation (MR) to investigate the causal effect of intrauterine exposure to greater maternal body mass index (BM...

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發表在:PLoS Med
Main Authors: Richmond, Rebecca C., Timpson, Nicholas J., Felix, Janine F., Palmer, Tom, Gaillard, Romy, McMahon, George, Davey Smith, George, Jaddoe, Vincent W., Lawlor, Debbie A.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5261553/
https://ncbi.nlm.nih.gov/pubmed/28118352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002221
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