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Using Mendelian randomization to determine causal effects of maternal pregnancy (intrauterine) exposures on offspring outcomes: Sources of bias and methods for assessing them

Mendelian randomization (MR), the use of genetic variants as instrumental variables (IVs) to test causal effects, is increasingly used in aetiological epidemiology. Few of the methodological developments in MR have considered the specific situation of using genetic IVs to test the causal effect of e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Wellcome Open Res
Prif Awduron: Lawlor, Deborah, Richmond, Rebecca, Warrington, Nicole, McMahon, George, Davey Smith, George, Bowden, Jack, Evans, David M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: F1000Research 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386135/
https://ncbi.nlm.nih.gov/pubmed/28405635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.10567.1
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