Using Genetic Variation to Explore the Causal Effect of Maternal Pregnancy Adiposity on Future Offspring Adiposity: A Mendelian Randomisation Study

BACKGROUND: It has been suggested that greater maternal adiposity during pregnancy affects lifelong risk of offspring fatness via intrauterine mechanisms. Our aim was to use Mendelian randomisation (MR) to investigate the causal effect of intrauterine exposure to greater maternal body mass index (BM...

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Pubblicato in:PLoS Med
Autori principali: Richmond, Rebecca C., Timpson, Nicholas J., Felix, Janine F., Palmer, Tom, Gaillard, Romy, McMahon, George, Davey Smith, George, Jaddoe, Vincent W., Lawlor, Debbie A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5261553/
https://ncbi.nlm.nih.gov/pubmed/28118352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002221
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