Using Genetic Variation to Explore the Causal Effect of Maternal Pregnancy Adiposity on Future Offspring Adiposity: A Mendelian Randomisation Study

BACKGROUND: It has been suggested that greater maternal adiposity during pregnancy affects lifelong risk of offspring fatness via intrauterine mechanisms. Our aim was to use Mendelian randomisation (MR) to investigate the causal effect of intrauterine exposure to greater maternal body mass index (BM...

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Détails bibliographiques
Publié dans:PLoS Med
Auteurs principaux: Richmond, Rebecca C., Timpson, Nicholas J., Felix, Janine F., Palmer, Tom, Gaillard, Romy, McMahon, George, Davey Smith, George, Jaddoe, Vincent W., Lawlor, Debbie A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5261553/
https://ncbi.nlm.nih.gov/pubmed/28118352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002221
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