Large-scale pharmacological profiling of 3D tumor models of cancer cells

The discovery of chemotherapeutic agents for the treatment of cancer commonly uses cell proliferation assays in which cells grow as two-dimensional (2D) monolayers. Compounds identified using 2D monolayer assays often fail to advance during clinical development, most likely because these assays do n...

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Mathews Griner, Lesley A, Zhang, Xiaohu, Guha, Rajarshi, McKnight, Crystal, Goldlust, Ian S, Lal-Nag, Madhu, Wilson, Kelli, Michael, Sam, Titus, Steve, Shinn, Paul, Thomas, Craig J, Ferrer, Marc
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5261027/
https://ncbi.nlm.nih.gov/pubmed/27906188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.360
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