Anti-proliferative activity of the NPM1 interacting natural product avrainvillamide in acute myeloid leukemia

Mutated nucleophosmin 1 (NPM1) acts as a proto-oncogene and is present in ~30% of patients with acute myeloid leukemia (AML). Here we examined the in vitro and in vivo anti-leukemic activity of the NPM1 and chromosome region maintenance 1 homolog (CRM1) interacting natural product avrainvillamide (A...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Death Dis
Principais autores: Andresen, Vibeke, Erikstein, Bjarte S, Mukherjee, Herschel, Sulen, André, Popa, Mihaela, Sørnes, Steinar, Reikvam, Håkon, Chan, Kok-Ping, Hovland, Randi, McCormack, Emmet, Bruserud, Øystein, Myers, Andrew G, Gjertsen, Bjørn T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260983/
https://ncbi.nlm.nih.gov/pubmed/27906185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.392
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados