Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease

Fbxo7 is a clinically relevant F-box protein, associated with both cancer and Parkinson's disease (PD). Additionally, SNPs within FBXO7 are correlated with alterations in red blood cell parameters. Point mutations within FBXO7 map within specific functional domains, including near its F-box dom...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biochem J
Main Authors: Teixeira, Felipe Roberti, Randle, Suzanne J., Patel, Shachi P., Mevissen, Tycho E.T., Zenkeviciute, Grasilda, Koide, Tie, Komander, David, Laman, Heike
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2016
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260939/
https://ncbi.nlm.nih.gov/pubmed/27503909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160387
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