Lysine 27 Ubiquitination of the Mitochondrial Transport Protein Miro Is Dependent on Serine 65 of the Parkin Ubiquitin Ligase

Mitochondrial transport plays an important role in matching mitochondrial distribution to localized energy production and calcium buffering requirements. Here, we demonstrate that Miro1, an outer mitochondrial membrane (OMM) protein crucial for the regulation of mitochondrial trafficking and distrib...

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Main Authors: Birsa, Nicol, Norkett, Rosalind, Wauer, Tobias, Mevissen, Tycho E. T., Wu, Hsiu-Chuan, Foltynie, Thomas, Bhatia, Kailash, Hirst, Warren D., Komander, David, Plun-Favreau, Helene, Kittler, Josef T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Molecular Bases of Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031514/
https://ncbi.nlm.nih.gov/pubmed/24671417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.563031
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