A novel crosstalk between CCAR2 and AKT pathway in the regulation of cancer cell proliferation

Human CCAR2 has recently emerged as having a pivotal role in the DNA damage response, promoting apoptosis and repair of heterochromatic DNA breaks. However, less is known about the function of CCAR2 in tumor formation and cancer progression. Here, we demonstrate, for the first time, that CCAR2 loss...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Restelli, Michela, Magni, Martina, Ruscica, Vincenzo, Pinciroli, Patrizia, De Cecco, Loris, Buscemi, Giacomo, Delia, Domenico, Zannini, Laura
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260903/
https://ncbi.nlm.nih.gov/pubmed/27809307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.359
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