A novel crosstalk between CCAR2 and AKT pathway in the regulation of cancer cell proliferation

Human CCAR2 has recently emerged as having a pivotal role in the DNA damage response, promoting apoptosis and repair of heterochromatic DNA breaks. However, less is known about the function of CCAR2 in tumor formation and cancer progression. Here, we demonstrate, for the first time, that CCAR2 loss...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Restelli, Michela, Magni, Martina, Ruscica, Vincenzo, Pinciroli, Patrizia, De Cecco, Loris, Buscemi, Giacomo, Delia, Domenico, Zannini, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260903/
https://ncbi.nlm.nih.gov/pubmed/27809307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.359
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