EZH2 mediates lidamycin-induced cellular senescence through regulating p21 expression in human colon cancer cells

Lidamycin (LDM) is a novel member of the enediyne antibiotics identified in China with potent antitumor activity. However, it remains unclear whether LDM has potential molecular targets that may affect its antitumor activity. Enhancer of zeste homolog 2 (EZH2) functions as a histone lysine methyltra...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Sha, Ming-Quan, Zhao, Xiao-Li, Li, Liang, Li, Li-Hui, Li, Yi, Dong, Tian-Geng, Niu, Wei-Xin, Jia, Li-Jun, Shao, Rong-Guang, Zhen, Yong-Su, Wang, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260875/
https://ncbi.nlm.nih.gov/pubmed/27882937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.383
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados