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Antitumor activity of anti-type IV collagenase monoclonal antibody and its lidamycin conjugate against colon carcinoma

AIM: Type IV collagenase including MMP-2 and -9 plays an important role in cancer cell invasion and metastasis and is an attractive target for mAb-directed therapy. The immunoreactivity of mAb 3G11, a mAb directed against type IV collagenase in human colorectal carcinomas, was studied by immuno-hist...

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Podrobná bibliografie
Vydáno v:World J Gastroenterol
Hlavní autoři: Li, Liang, Huang, Yun-Hong, Li, Yi, Wang, Feng-Qiang, Shang, Bo-Yang, Zhen, Yong-Su
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Inc 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398695/
https://ncbi.nlm.nih.gov/pubmed/16052675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i29.4478
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