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Activation and cleavage of SASH1 by caspase-3 mediates an apoptotic response

Apoptosis is a highly regulated cellular process that functions to remove undesired cells from multicellular organisms. This pathway is often disrupted in cancer, providing tumours with a mechanism to avoid cell death and promote growth and survival. The putative tumour suppressor, SASH1 (SAM and SH...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Burgess, Joshua T, Bolderson, Emma, Adams, Mark N, Baird, Anne-Marie, Zhang, Shu-Dong, Gately, Kathy A, Umezawa, Kazuo, O'Byrne, Kenneth J, Richard, Derek J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260870/
https://ncbi.nlm.nih.gov/pubmed/27831555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.364
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