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Spin models inferred from patient-derived viral sequence data faithfully describe HIV fitness landscapes
Mutational escape from vaccine-induced immune responses has thwarted the development of a successful vaccine against AIDS, whose causative agent is HIV, a highly mutable virus. Knowing the virus’ fitness as a function of its proteomic sequence can enable rational design of potent vaccines, as this i...
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| izdano v: | Phys Rev E Stat Nonlin Soft Matter Phys |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5260469/ https://ncbi.nlm.nih.gov/pubmed/24483484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1103/PhysRevE.88.062705 |
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